منابع مشابه
Active Gel Model of Amoeboid Cell Motility
We develop a model of amoeboid cell motility based on active gel theory. Modeling the motile apparatus of a eukaryotic cell as a confined layer of finite length of poroelastic active gel permeated by a solvent, we first show that, due to active stress and gel turnover, an initially static and homogeneous layer can undergo a contractile-type instability to a polarized moving state in which the r...
متن کاملAssessing neural stem cell motility using an agarose gel-based microfluidic device.
While microfluidic technology is reaching a new level of maturity for macromolecular assays, cell-based assays are still at an infant stage. This is largely due to the difficulty with which one can create a cell-compatible and steady microenvironment using conventional microfabrication techniques and materials. We address this problem via the introduction of a novel microfabrication material, a...
متن کاملImproved agarose gel assay for quantification of growth factor-induced cell motility.
Cell chemotaxis is frequently required in normal or pathological situations such as invasion, metastasis, and tumor angiogenesis and may involve many different cell types. At present, no device can simultaneously (i) make morphological observations, (ii) quantify cell migration, (iii) test multiple chemoattracting gradients, and (iv) analyze cell-cell interactions. We developed an agarose-based...
متن کاملCELL MOTILITY Historical Development of Cell Motility
In the first half of the 20 century, it was generally accepted that myosin and actin are proteins specific for muscle, and muscle contractility is a specific interaction of actin, myosin and ATP. It came as a surprise when in 1954 Hoffmann-Berling reported that water-glycerol extracted amnion fibroblasts contract upon addition of ATP. Figures CM1a and 1b show that the elongated fibroblast cells...
متن کاملThyroxin Is Useful to Improve Sperm Motility
Objective The aim of this study was to evaluate the non-genomic action of thyroxin on sperm kinetic and its probable use to improve sperm recovery after applying an enrichment method like “swim-up” in comparison with the available one, pentoxifylline. MaterialsAndMethods This is an experimental study. A total of 50 patients were recruited, followed by infertility consultation. Conventional sper...
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ژورنال
عنوان ژورنال: Nature
سال: 1977
ISSN: 0028-0836,1476-4687
DOI: 10.1038/270560a0